Connor Scott is a seasoned neuroscientist with over 11 years of specialized expertise in ex vivo investigations, including extensive human tissue research, molecular biology, and mass spectrometry.
His career has been dedicated to unraveling the molecular complexities underlying neurodegenerative diseases through innovative research projects and drug discovery programs. His proficiency spans the fields of histology, neuropathology, neurobiology, and various multi-omics techniques.
He specializes in the following indications: Alzheimer’s Disease, Parkinson’s Disease, Frontotemporal Dementia, Amyotrophic Lateral Sclerosis, Narcolepsy, Schizophrenia and Glioblastoma Multiforme.
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D.Phil/PhD in Clinical Neurosciences, 2021
University of Oxford
BSc (Hons) in Biomedical Sciences, 2012
University of Greenwich
Frontiers in Neuroanatomy publishes research revealing important aspects of the anatomical organization of all nervous systems across all species.
Frontiers in Neuroimaging is a multidisciplinary journal focused on expanding research on the physiological principles underlying typical and atypical brain functions to decrease the global burden of brain disorders.
Digital microscopist for these historic collections.
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President of graduate students at one of University of Oxford’s colleges - Somerville College.
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Responsible for planning, budgeting, and executing social activities at Somerville College.
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The Neuropathology EQA scheme (NEQAS) forms part of a national system of quality assurance to healthcare organisations that is being maintained and improved.
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With regards to scientific papers, MogoEdit provides two editing models: standard polishing and in-depth editing. Standard paper polishing mainly focuses on correcting errors in language, including word use, expressions, grammar, and sentence structure.
The aim is to show what clinical researchers in Oxford are doing to improve diagnosis and care. The event is organised in partnership between the Nuffield Department of Clinical Neurosciences and the Cancer Research UK Oxford Centre, and is supported by the NIHR Oxford Biomedical Research Centre and the Brain Tumour Charity.
London International Youth Science Forum The London International Youth Science Forum (LIYSF) is a two week residential student event held at Imperial College London & The Royal Geographical Society, with lecture demonstrations from leading scientists, visits to world class laboratories and universities combined with cultural interaction, with 500 students aged 16-21 years old from 70 countries.
Oxford Hands-On Science (OxHOS) is a student-run society based in Oxford. We believe that science is fun and relevant to everyone. We spread our enthusiasm for science to children and their families by taking a range of hands-on experiments into schools and public venues, with helpful undergraduate and post-graduate student volunteers explaining the science behind them.
Degeneration of the primary motor cortex is a defining feature of amyotrophic lateral sclerosis (ALS), which is associated with the accumulation of microscopic protein aggregates in neurons and glia. However, little is known about the quantitative burden and pattern of motor cortex proteinopathies across ALS genotypes. We combined quantitative digital image analysis with multi-level generalized linear modelling in an independent cohort of 82 ALS cases to explore the relationship between genotype, total proteinopathy load and cellular vulnerability to aggregate formation.
While nearly comprehensive proteome coverage can be achieved from bulk tissue or cultured cells, the data usually lacks spatial resolution. As a result, tissue based proteomics averages protein abundance across multiple cell types and/or localizations. With proteomics platforms lacking sensitivity and throughput to undertake deep single-cell proteome studies in order to resolve spatial or cell type dependent protein expression gradients within tissue, proteome analysis has been combined with sorting techniques to enrich for certain cell populations. However, the spatial resolution and context is lost after cell sorting. Here, we report an optimized method for the proteomic analysis of neurons isolated from post-mortem human brain by laser capture microdissection (LCM).